The differential diagnosis should consider and exclude the usual pseudo-scabies, as well as any form of usual bacterial or other fungal skin infections. Infections with "Staphilococcus aureus" bacteria can show initially similar symptoms and they may be, sometimes, involved too. Worse are infections with MRSA (multi-resistant staphilococcus aureus) which leads mostly to death or amputations if not recognized and treated in the first days with newer or higher antibiotic treatments.

The immune competence of the patient also plays a role, of course, in the sort of physical expression of this infection. A weak immune system and a certain chemical body condition e.g. hormonal and granulozytes lack are playing a major role in immunity against parasites and invasive fungal infections. A decrease of total granulocyte counts in peripheral blood (below 1000 /mm3 ) has been recognized to be a crucial risk factor for the acquisition of similar fungal infections.

A former tick bite and infections with all typical involved bacterias (babesia, ehrlichea, rickettsia, anaplasma etc.), may be also a reason for a lower level of granulozytes, which is reducing in common the immunity against external parasitical infections, as well the morgellons infection.

But a direct substitution of granulocytes in immunocompromised patients has in most cases failed to prove efficacious. As well predisposing factors like Diabetis mellitus, a former Corticosteroid therapy, Neutropenia, constant stress (cortisol), metabolism disorders, surgery trauma, and a malnutrition is mostly decisive for an occurrence of the pathogen`s symptomatology. But it can occur also in healthy patients in the presence of insignificant trauma.

Also the immune response to the antigens of this parasite occurs, basically, like that with other parasitic infection: induction phase, delayed hyper sensitivity, direct hyper sensitivity and sometimes later also with a desensitization.

The initial inoculation of parasites often takes place on hairy areas, or on bare skin patches. In both areas large abscess-like lesions, blister lesions, or pimple development, as well as skin rash can appear either within 3-14 days after exposure, or even during the first day of infestation. This is usually related to the relative size, the number and the different kinds of carried pathogens of the initial infesting parasites and if the contact happend over the skin or internally by swallowing.

It is possible, as well, that they can live undiscovered in the host body for a certain time. Some situation or a certain food can provoke them, like a trigger reaction such as with herpes, and then the manifestation of them is recognizable in typical skin symptoms. The difference between considerated "HEALTHY PEOPLE" and evidently infected persons might be, that in common some are reacting more allergical then others to such infections. Surely also healthy people may have morgellons but it takes longer to manifest skin or internal symptoms.

Also the patient's history concerning his living conditions must be investigated; to clarify issues concerning possible re-infection such as sexual practices, occupation, and household pets. Previously one limited investigation on the predictability for infected areas between the fingers and the backs of the hand, may have led investigators to be circumspect in their physical exams for these types of infection. This exam is surely not adequate for these new parasites, since the patient populations are NOT comparable since the study included mostly unsanitary, neglected individuals with a proven Scabies infection.

Therefore, if there is suspicion for infection with this new parasite, the whole body should always be examined. This includes, but is not limited to: external upper arms, shoulder areas, lumbar region, inside thigh, as well as the nasal cavities, ear canals, etc. (see also process of infection)

Indeed many reports on this illness demonstrate initially a scabies-like behavior and skin distribution, with all typical preliminary signs, such as, even the skin scars that can be seen after an infestation. Yet, in this new infection, sooner or later, these are eventually changed, bit by bit, to the much more atypical areas (nose, scalp etc.) that are commonly preferred by Morgellons.

If the pimples or nodular lesions frequently form around the eyebrows, upper and lower eyelids and on the forehead area, or in general in the facial area as well as on the scalp, especially in the nares and on the nose, and on occasion also throughout the whole body; then one can presume this to be an infestation of the new parasite, and therefore exclude any typical Scabies infestation.

Although the Scabies Norvegica strain shows atypical behavior patterns, as well as it causes initial similar illness symptoms and its lesions always move in the direction toward the head area, however it is seldom discovered within the nose, mouth and eyes.

A typical infestation zone around the eyes and orbits depends mainly upon the individual behavior of pet host-parasites interaction, and the strain which originates on the infested animal. These include factors such as the typical eye-glass outlines/contours, due to loose hairs, or pressure on certain follicles. At any rate, these parasites do prefer to expand their infestation, around the eyes, nose, mouth and ears.

In the case of an infestation of a human host, one usually sees eyeglass outline/contour in the form of skin lesions and pimples around the ocular parts/forehead and also the eyebrows and eyelashes are not spared. In the morning, it can be observed that the eyelashes are sometime stuck together. However, they are only temporary human parasites.

Of course also the hair bellows mite (Demotex folliculorum) causes similar symptoms, especially with acne patients. These mites also live in suet/tallow glands and pathologically seen, they influence in general the clinical picture by her contribution.

These first typical signs cannot count only as an indicator, but also as the propagation trend in the direction of scalp, face, ears and nose. Because in general also around the nipples, the backs of the hand, between fingers and all the other areas which generate sweat, will be the favorite areas where it can be found later.

The external symptoms particullary with an infestation on the hairs are noticeable that they will turning whitish and the hair will looks rather glassy and transparent as it turns grey in the usual form. It looks rather like an exhausted and transparent straw.

On occasion one also sees under the shoulders hairs eggs sticking near the base of the hairs. Always in the lower area, the eggs are looking like added chain files which probably remind of a louse behaviour. These are also discoverable in the eyelashes and between anus and genitals, and other obvious tracks from the parasites too.

It seems generally that this organisms prefers the contents of the hairs (keratin, protein/collagen) which are one of their main food sources. Therefore an Alopecia always come along (scalp, eyebrows, eyelashes, legs), which is also a very atypical Scabies behavior, but a typical fungal behavior.

Additionally a loss of sight (blur) and degradation of the eyes with inflammations/infections and increased luminous sensivity. A general poorer visibility is common due to the bacterial (keratitis) and mycotical biofilm (keratomycosis) on the retina (cornea). These eye symptoms infestation in the front and rear ocular segments, retina (temporary flashs/lightings) and on the cornea are caused from organisms which flow out of the lymph system, which ends also around the eyes.

However, perhaps due to different kinds of bacterial/fungal infections or various genetic DNA portions (if we assume one organism) there are connections to other fungal life forms e.g. Endomorphthoraceae/Mucoraceae/Zygomycetes, Aspergillus spp., or bacterias with kinds of Staphilococcus, Streptococcus and or to customary worm/nematods infestation with a quite similar symptomatology. In general, any kind of pathogens can be involved !!

Starting in general with lesions, pimples and knods on the skin, as well as swelling of the lymph nodes, formation of wrinkles of the skin and pigment disturbances, as well as numbness/tingling of the extremities and also an increasing visual disturbances of the eyes (cornea/callosity, clouding, constant loss of eye sights and blindness). An acute illness runs first with chills or heat flushes, as with hormonal disorder too.

These symptoms are released also by the immune response of the human body. The outbreak of the chronic illness after an infection amounts on an average of 4-8 months or longer.

In the further process there occurs an encapsulation of the micro organisms which leads to connective tissue nodes with inflammatory Granuloms, with general skin symptoms like skin edema, itch, papulosa Exanthema and Lymphadenitis. (see symptoms)

Later follows a chronic Dermatitis, depigmentation of the skin (bright spots), Lichenification and atrophy. Cellulitis and flabby border skin folds with hanging lymph nodes can occur too, and sclerosiatic Lymphadenitisas.

similar to a diffuse systemic scleroderma caused from Borrelia burgdorferi infection.

Internal symptoms are causing in a later stage of infection a general physical weakness which is common among concerned, also a reduced efficiency, chronic fatigue syndrome accompanied by concentration problems and neurological signs as Fibromyalgy, MS and also Meninigitis/Encephalitis. As well a state of heightened anxiety, mood swings, angryness, resignation, depression, apathy and often suicide minds.

Watch also this video about lyme and co-infections

Sometimes having gastrointestinal difficulties (failure), unexplainable back pain, coughs, rigid neck and other parts and progressive parodontal disease (tooth decay) and gum detoriations.

Similar symptoms and particullary Meninigitis/Encephalitis might be caused not only from lyme but mostly from viruses as Varizella, Coxsackie, Enterovirus, EBV (Ebstein-Barr Virus), Herpes simplex Typ 2, LCM-virus, HIV. As well from other bacteria such as Enderobacteria (E.coli), Mycoplasma, Clamydia pneu.,  Streptococcus group B, and Listeria monocytogenes.

Particullary with babys, children or immunosuppresive people, or infections with Meningococcus or Pneumococcus in healthy people. As well fungi (Aspergillus spp.) and parasites (Naegleria fowleri) can cause similar symptoms. 

The morgellons organisms live initially if swallowed by mouth internally or in the nose and mouth areas, as well on the skin. There is a tendency to settle on the skin and hairs and in the subcutaneous connective skin tissue (collagen and fat cells), perhaps because the fiber particles are forced out internally from the human lymph system or because it is wanted from them for recreation or to reach oxygen or moistened skin areas which are generally preferred. (more information).

In a later stage of an infestation due to an increasing amount of internally accumulated micro organisms also perhaps an invasion (spiderweb-like slimy tubuli) of internal host areas can occur. (lung, nerves, organs, gut, brain). Different further complications can follow (thrombosis, heartache etc.) due to an ongoing process of converting and plastification of the host cells.

More exact microscopic investigations result in clarity and are always compellingly necessary therefore. It is also always advisable if symptoms are lacking, if difficulty making the correct diagnosis, or recognition of the severity of the infestation, then one must receive a skin scrabing, or adhesive tape sampling, whatever results in better success in the recognition.

This should be especially helpful particullary if this specimen sample was taken directly at the infestation sites. Almost always there will be some external parasites and larvae, or ova (eggs) or at least unusual fibrous matter easly seen under microscop at 100-200X magnification.

However, one should know in addition what one actually should do with for which findings and what one must look for. If an scrabing or a withdrawal sample by needle brings a kind of coloured fuzz, then that maybe the only "parasite" you will be able to recover and you should accept this. Further samples could be attempted to try for more statistical significance, in order to exclude coincidences. Further measures should then be immediately initiated after positive findings.

Treatment Implementation (See also the M-R-O Protocol)

Especially on suspicion with these new parasites, usual and uncommon laboratory tests should be immediately initiated (Lyme Borreliose, Clamydia pneu., Streptococcus pneu., Mycoplasma, Mycobacteria, Babesia, fungi etc.). The lower table gives a small overview of the usual investigations and medications which were given normally by knowledgeable caregivers. Particularly with Lyme/Borreliosis, depending on infestation stages different antibiotic therapies are prescribed (see also under Lyme).

Don`t use Lindan, Perimethrin, Sulphur, or any other insecticidal cream, because the symptoms get worse.

Using the DNS standard test by means of the Polymerase-chain-reaction (PCR), until recently, PCR's have been used as a good means for detection of many un-identified parasitical infections, as well as their identification by means of certain customary blood tests (Sero-diagnostic). However, now some of these tests for the antigens of parasites have, unfortunately, become outdated because there are so many new strains and species of parasites and many parasites antigens were still not isolated yet.

One could also perform blood tests of these parasites with the use of recombinant antigens specifically directed against Protozoan, Helminthes, as well as other parasites of the internal organs. However, this could become also quite difficult, because presently there have been no antigens isolated from this multi life form. In addition, usual testing (Lyme) should occur at least 6 weeks after exposure, in order to insure adequate time for an immune response to be demonstrated on clinical test findings.

Even blood tests by Elisa test procedure, or using IgG, with Morgellons and its co-enzymes of infection (bacteria etc.) will not show always usual clinical findings, such as can happen with Borrelia (Lyme), the main pathogen bacteria of morgellons. Because scientists have already found out that the exciters can be encapsulated into human tissue or the exciters create their own cysts, to avoid detection and survive there inside the cysts for a prolonged time, and no clinical results can be found. For Lyme, better results have been found with the Bowen test or the Western Blot test technology used by "IGenex" of Palo Alto, CA.. To read more about this on the Internet, see www.igenex.com.

As well the very promising new intracellular LTT- Melisa test (Lymphozyt-Transformation-Test) is slowly becoming established. It bring more positive results then the other usual tests. It is measuring the cellular defence and shows always an exposition in intracellular stages and also if the infection is new or much older.

For being 95 % sure of a borrelia infection, the newest German test called T-Cellspot is actually the best on market. The T-Cellspot test with the Elispot-Assay (Enzyme Linked Immuno Spot Assay) is based on the research of antigene-specific zytokin-secretion through reactive Lymphozyts.

The T-Cellspot test is actually 200 time more sensitive than the older elisa test. As well it can show pretty soon after an infection (2-3 weeks) a seropositive result and therefore an earlier medical treatment can be started to prevent usual damage, due to a lack of quick recognition of borrelia. (read more here). For chronic lyme also the CD57 test can be used now.

Or see the M-R-O protocol with more medications

Exactly this non sterility is causing most internal symptoms due to imported bacteria or fungi and perhaps viruses too, what we must fight primarly and then the polymers which can be accumulated in the human body and causing other illness symptoms (hormonal disorders etc.).

Prognosis:

At an advanced stage of infestation of the host organism after approximately 12-24 months, it may be possible to have an infestation of all human protein/fat cells and internal organs, the lymph system, the blood circulatory system, urinary and respiratory tract, or any other human body cavities and cells.

A rapid diagnosis and treatment in the initial phase of the infection, may prevent in any case the usual pathogensis. If allowed to progress a higher pathological damage is added (probably not ). This is caused, by absorbation and converting (metabolism) of the host proteins or by an enzymatic process too. The usual metabolism-products of these parasites is plastic-chitin-like biomass, fibers and toxins also from the own opportunistic fungal, bacterial or viral pathogens.

Therefore an initial oral application (antifungal, antibiotica) or after an already longer existing infestation a subcutan antibiotic injection is more indicated, in order to work against a further disease process. Because the pathogenetic consequences of this invasion is unforeseen and most likely incurable and irrversible in further process (nerves, heart, liver and brain damage).

For an infected person each day counts in order to fight against the total invasion and plastification of the body. Antibiotics as Minocycline, clarythromycin, Azithromycin, Roxytromycin or Bactrin are the first choice of recommanded treatments. In order to understand Morgellons, what we are fighting in the first instance, are any kind of rare entomopathogenic fungus and bacteria such as borrelia, mycoplasma and opportunistic bacteria e.g. E. coli, Pseudomonas, Streptoccocus etc., and secondly other fungi (dermatophytes) and viruses, and surely the fiber remains. Perhaps various insectal infestations too, which been attracted from the morgellons pheromons.

Antibiotics can`t be a permanent remedy, only in the beginning and should be reduced after a few month to prevent a damage of the liver and kidneys. Natural remedies should be added later too.

In summation: Some, which had this skin problems, may be cleared up and so that one can go again amongst humanity. Some acute or chronic lyme symptoms, may be surely take longer to cure than the external skin manifestations which are just the top of an iceberg. The Morgellons syndrome is multi-systemic and not a skin disease!! The skin symptoms are just an expression of it. Regarding my own theories, the Morgellons syndrome is actually just a systemic mycosis caused from bio-insecticides which can pass also borrelia and other pathogens collected or absorbed before contaminating mammals.

Since these polymers (plastic, chitin, cellulosis) are pleo-vectors for multiple pathogens, some have been tested but not everybody have been proven with some of these viral, mycotical and bacterial or opportunistic involved pathogens, but most concerned have been infected with "Borrelia burgdorferi" (Lyme).

Adeno-Virus

Actinomycetes

Giardia

Aspergillus

Acanthamoeba

WA-1 (Babesia-like)